Cryptogenic Gelastic Seizures from Medial Frontal Area: 2 Cases

J Korean Neurol Assoc > Volume 20(6); 2002 > Article

Journal of the Korean Neurological Association 2002;20(6): 716-720.

내측 전두엽에서 기원한 잠복성 홍소발작 2예

문소영 , 서대원 ·김한영 ·홍승철 ·홍승봉

성균관대학교 의과대학 삼성서울병원 신경과학교실,신경외과학교실

Cryptogenic Gelastic Seizures from Medial Frontal Area: 2 Cases

So-Young Moon, M.D.

"Departments of Neurology and Neurosurgery, Samsung Medical center, Sungkyunkwan University School of Medicine"

Abstract

"Little has been known about what pathways subserve mirth and its expression laughter. We report two patients with cryptogenic gelastic seizures who provide some insight into the mechanisms of laughter. Invasive video-EEG monitor-ing showed ictal onset zone to be either in the left or right medial frontal cortex. After resection of the medial frontal area, including the epileptogenic focus, patients have been in gelastic seizure-free state. This suggests the possibility that medial frontal cortex is involved in the motor act of laughter.Key Words : Gelastic seizures, Invasive EEG monitoring, Medial frontal cortex"