J Korean Neurol Assoc > Volume 20(4); 2002 > Article

Journal of the Korean Neurological Association 2002;20(4): 407-409.

Carbamazepine 에 의해 발생한 심각한 서맥성 부정맥 2예

손종희, 마효일 김대훈 유경호 정승철 이병철

한림대학교 의과대학 신경과학교실

"Two Cases of Carbamazepine Induced Bradyarrhythmia :Potentially Lethal Side Effect in Elderly Patients"

Jong Hee Sohn

Department of Neurology, Hallym University College of Medicine

Abstract

"Although potential hematologic complications of carbamazepine (CBZ) have been well known, the cardiac effects of CBZ are not widely appreciated. We report two cases of severe bradyarrhythmia induced by the usual dosage of CBZ. Two elderly patients complained of chest discomfort and dyspnea after CBZ medication. Their EKGs showed sinus bradycardia with junctional escape rhythm. After the discontinuation of CBZ, cardiac conduction abnormality were resolved. Even though cardiac side effect of CBZ is rare, it is potentially lethal in elderly patients. Key Words : Carbamazepine, Arrhythmia, Heart conduction"