J Korean Neurol Assoc > Volume 20(3); 2002 > Article

Journal of the Korean Neurological Association 2002;20(3): 283-286.

"뇌병변이 있는 간질 환자에서 항경련제 부작용으로 발생한 편측성 낙하진전 2예"

조아현 , 이상암

울산대학교 의과대학 서울아산병원 신경과학교실

"Unilateral Asterixis Induced by Antiepileptic Drugs in Epileptic Patients with Structural Brain Lesion"

A-Hyun Cho, M.D.

Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine

Abstract

"It is well recognized that antiepileptic drugs (AEDs) can cause generalized or bilateral asterixis. However, the unilat-eral asterixis induced by AEDs has been rarely reported in patients with structural brain lesions. We report 2 patients who developed unilateral asterixis within therapeutic AEDs levels. In both patients, the unilateral asterixis disappeared when the daily dosage of AEDs was decreased. Our cases suggest that the cerebral hemisphere with structural lesions might be more vulnerable to the development of AEDs-induced asterixis.Key Words : Unilateral asterixis, Antiepileptic drugs, Structural brain lesions"