J Korean Neurol Assoc > Volume 20(3); 2002 > Article

Journal of the Korean Neurological Association 2002;20(3): 243-247.

"파킨슨병 환자의 체감각 신경 및 운동신경 유발 전위 검사"

최선아 , 임성룡 이준홍

국민건강보험공단 일산병원 신경과

"Somatosensory and Motor Evoked Potentials in Parkinson s Disease"

Sun-Ah Choi, M.D

National Health Insurance Corporation Ilsan Hospital, Department of Neurology

Abstract

"Background: There are conflicting reports on the attenuationof the frontal N30 component of the median nerve derived somatosensory evoked potentials(MN SSEP) and the P37-N45 component of the posterior tibial nerve derived somatosensory evoked potentials(PT SSEP) in Parkinson s disease(PD). The central motor conduction time(CMCT) and the threshold of the magnetic motor evoked potentials(MEP) in PD also demonstrate inconsistent results. Methods : We studied MN SSEP, PT SSEP and MEP in 10 patients with PD and compared them with 10 normal controls. Results : The latency and amplitude of MN SSEP was normal in the patients with PD and, in particular, the frontal N30 compo-nent was not significantly depressed. There was no difference between the PD patients and the normal controls in the CMCT and the amplitude of arm and leg MEP. But compared with the normal controls, the latency of P37 cortical evoked potentials was prolonged and transmagnetic stimulation(TMS) threshold for evoking responses in relaxed or active tibialis anterior muscle decreased in the patients with PD. Conclusions : Recording of MEP threshold in tibialis anterior muscle and P37 latency of PT SSEP may be useful for the evaluation of patients with PD.Key Words : Parkinson s disease, Somatosensory, Motor, Evoked potentials"