J Korean Neurol Assoc > Volume 20(1); 2002 > Article

Journal of the Korean Neurological Association 2002;20(1): 79-81.

LamotrIgine과 연관된 항경련제 과민증후군 3예

조용원 , 이이형 손성일 정두교 임정근 이상도

계명대학교 의과대학 신경과학교실

"Three Cases of Anticonvulsant Hypersensitivity Syndrome Associated with Lamotrigine"

Yong-Won Cho

Department of Neurology, Keimyung University, School of Medicine

Abstract

"Among the various side effects of anticonvulsant medication, the anticonvulsant hypersensitivity syndrome (AHS) is underrecognized. This condition developed frequently with aromatic anticonvulsants, but with new antiepileptic drugs as well. We experienced three lamotrigine-induced AHS cases with symptoms such as fever, rash, leukopenia, eosinophilia and lymphadenopathy, which subsided after withdrawal of lamotrigine.Key Words : Anticonvulsant hypersensitivity syndrome, Lamotrigine"

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