J Korean Neurol Assoc > Volume 19(6); 2001 > Article

Journal of the Korean Neurological Association 2001;19(6): 573-578.

경동맥 내막중막두께와 주간동맥 경화성 뇌경색

이영배, 강성수 박현미 신동진

가천의과대학교 길병원 신경과학교실

"Carotid Artery Intima-Media Thickness and Large-Artery Atherosclerotic Cerebral Infarction"

Young-Bae Lee, M.D., Sung-Soo Kang, M.D., Hyeon-Mi Park, M.D., Dong-Jin Shin, M.D.

Department of Neurology, Gachon Medical School, Gil Medical Center

Abstract

"Background : Carotid artery intima-media thickness (IMT) is an early structural marker of the atherosclerotic processes and an increased carotid IMT is a strong predictor of stroke. The measurement of carotid IMT is a useful non-invasive measure in risk stratification of ischemic stroke. The objective of the present study is to evaluate whether mea-surement of carotid IMT contributes to the prediction of large-artery atherosclesrotic cerebral infarction. Methods : By TOAST classifications, 88 patients with ischemic stroke [67 with large-artery disease (LAD) and 21 with small-artery disease (SAD)] were selected from a stroke registry (2000.7~2001.7). Carotid IMT was defined as the mean of IMT measured by B-mode ultrasonography (12 MHz linear probe) at 10 sites of both distal common carotid arteries. The dif-ferences of carotid IMT were analyzed statistically between the LAD and SAD groups according to age or sex. Results : The carotid IMT was 0.84±0.08 mm for the LAD and 0.77±0.04 mm for the SAD groups. There were no statistically significant differences (p>0.05) of carotid IMT(total, age, sex) between the LAD and SAD groups. Conclusions : In this study, the carotid IMT was not associated with LAD as wells as SAD. However, with the increase in age, there is a tendency to increase the differences of carotid IMT between LAD and SAD groups. Key Words : Carotid intima-media thickness (IMT), Large-artery atherosclerosis"