| 전기진단학적 분류에 따른 길랑바레 증후군 아형의 임상양상 |
| 김주동, "김민기이김지연이안진영이김병준*이김주용
†" |
| 지방공사 강남병원 신경과,성균관대학교 의과대학 삼성서울병원 신경과*,강원대학교 신경과 |
| Clinical Characteristics of the Subtypes of Guillain-Barre Syndrome according to the Electrodiagnositic Criteria |
| "Joo Dong Kim, M.D., Min Ky Kim, M.D., Jin Young Ahn, M.D., Ji Youn Kim, M.D.,
B.Joon Kim, M.D.*, Joo Yung Kim, M.D.
†" |
| "Department of Neurology, Kangnam General Hospital Public Corporation,
Sungkyunkwan University School of Medicine, Samsung Medical Center*
Department of Neurology, Kangwon National University School
†" |
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| Abstract |
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"Background : Guillain-Barre syndrome (GBS) is defined as a recognizable clinical entity that is characterized by
rapidly evolving symmetric limb weakness, loss of tendon reflexes, absent or mild sensory signs, and variable autonom-ic
dysfunctions. Recently, GBS has been classified as a classical demyelinating (acute imflammatory demyelinating
polyradiculoneuropathy, AIDP) and two axonal (acute motor axonal neuropathy, AMAN, and acute motor sensory
axonal neuropathy, AMSAN) forms. The clinical pattern and prognosis according to type is not clear. Methods : Forty-one
patients clinically diagnosed as GBS were enrolled and classified as AIDP, AMAN, and AMSAN according to
electrodiagnostic criteria. We analyzed the clinical data of each subgroup; age, sex, seasonal distribution, history of pre-vious
illness, cranial nerve involvement, respiratory involvement, and motor weakness. R e s u l t s : Forty-one patients
with GBS were comprised of 19 patients (46.3%) with AIDP, 12 patients (29.2%) with AMAN, and 10 patients (24.3%)
with AMSAN. AIDP was found more frequently in males and in winter (42.1%) while axonal forms of GBS showed
neither gender nor seasonal predominance. Frequency of cranial nerve involvement was not different between the sub-groups
of GBS, whereas respiratory involvement was more frequent in AMSAN (50%). Upper limbs were weaker in
axonal than in demyelinating types of GBS. Conclusions : Axonal forms of GBS showed some clinical characteristics distinctive from the demyelinating forms, which might be useful in the differential diagnosis of subgroups of GBS. J Korean Neurol Assoc 19(5):503~508, 2001Key Words : Guillain-Barre syndrome, Acute imflammatory demyelinating polyradiculoneuropathy, Acute motor axonal neuropathy, Acute motor sensory axonal neuropathy" |
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