| 쯔쯔가무시병에 의한 뇌막염 2예 |
| 김인규, 이성철*·김준우*·서강석*·박홍배*·이승택†·김병채‡·김명규‡·조기현‡ |
| 목포중앙병원 신경과,내과*,일반외과†, 전남대학교 의과대학 신경과학교실‡ |
| Two Cases of Tsutsugamushi Meningitis |
| In-Gyu Kim, M.D., Seong-Cheol Lee, M.D.*, Joon-Woo Kim, M.D.*, Kang-Seok Seo, M.D.*, Hong-Bae Park, M.D.*, Seung-Taeck Lee, M.D.†, Byung-Chae Kim, M.D.‡, Myeong-Kyu Kim, M.D.‡, I-Hyun Cho, M.D.‡ |
| Department of Neurology, Medicine*, and General Surgery†, Mokpo Jung-ang General HospitalDepartment of Neurology, Chonnam University Medical School‡ |
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| Abstract |
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Meningitis associated with tsutsugamushi is not a rare disease and simple, effective treatments are available. However, the diagnosis of meningitis is important since it is potentially associated with significant mortality rates. Case 1 : A 47-year-old woman had a headache and high fever with chills for 3 days. She fell into a stupor, and her blood pressure dropped to 80/60 mmHg on the fifth day of admission to the hospital. The patient was treated with 200 mg of doxycycline given intravenously. Case 2 : A 48-year-old woman was admitted with a 7-day history of fever with chills, severe headache, vomiting, and a generalized non-pruritic erythematous maculopapular rash. The patient was treated with 200 mg of doxycycline given orally. CSF examinations revealed predominantly lymphocytic pleocytosis in all cases. The indirect immunofluorescent antibody titer for Orientia tsutsugamushi were 1:20,480 in case 1 and 1:5, 120 in case 2. We report two cases of meningitis associated with tsutsugamuschi disease.
J Korean Neurol Assoc 18(5):642~644, 2000
Key Words : Meningitis, Orientia tsutsugamushi, Doxycycline |
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