Serial MRI Findings in a Clinically Diagnosed Adult Onset Leigh Syndrome

J Korean Neurol Assoc > Volume 18(3); 2000 > Article

Journal of the Korean Neurological Association 2000;18(3): 341-344.

임상적으로 진단된 성인에서 발병한 Leigh 증후군에 있어서 연속적인 MRI 소견

김성은 김재영 정정욱 김동선 정은주 김응규 손석현*은충기*이태윤, 김성은 김재영 정정욱 김동선 정은주 김응규 손석현*은충기*이태윤

인제대학교 의과대학 신경과학교실,방사선학교실*,동래 봉생병원 신경과

Serial MRI Findings in a Clinically Diagnosed Adult Onset Leigh Syndrome

Serial MRI Findings in a Clinically Diagnosed Adult Onset Leigh Syndrome Sung Eun Kim, M.D., Jae Young Kim, M.D., Jung Wook Jung, M.D., Dong Sun Kim, M.D., Eun Ju Jung, M.D., Eung Kyu Kim, M.D., Seok Hyun Son, M.D.*, Choong Ki Eun, M.D.*, Tae Yoon Lee,

Department of Neurology, Department of Radiology*, Pusan Paik Hospital, Inje University Department of Neurology

Abstract

Adult onset Leigh syndrome is a very rare neurodegenerative disorder of unknown cause. We report the evolution of the lesions on serial MRIs in a 38-year-old man with clinically diagnosed Leigh syndrome. We emphasize that the mammillary bodies can be involved during the disease course and that premortem diagnosis of Leigh syndrome is pos-sible, if a characteristic distribution of lesions can be demonstrated on MRI. J Korean Neurol Assoc 18(3):341~344, 2000 Key Words : Leigh syndrome, Mammillary body, MRI