| 6 0세 이상의 노인에서 시작된 경련 : 입원 환자를 대상으로 |
| 고임석, 송홍기 ·김진혁 ·김형철 ·황성희 ·권기한 ·배재천 ·이병철 |
| 한림대학교 의과대학 신경과학교실 |
| Newly Onset Seizures in the Elderly : A Hospital-based Study |
| Im-Seok Koh, M.D., Hong-Ki Song, M.D., Jin-Hyuck Kim, M.D., Hyoung-Cheol Kim, M.D., Sung-Hee Hwang, M.D., Ki-Han Kwon, M.D., Jae-Chon Bae, M.D., Byung-Chul Lee, M.D. |
| Department of Neurology, Hallym University College of Medicine |
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| Abstract |
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Background : Increasing incidences of epilepsy in the elderly are well-known. However, the causes of newly onset seizures in the elderly have rarely been described in Korea. Methods : We selected 160 cases of individuals who had their first seizure at over the age of 60 (male : female = 1.5 : 1 ; mean age : 69.1 years), who were admitted to Hallym University Hospital from July 1, 1994 to June 31, 1998. We analyzed the etiology, type of seizures, EEG, neuro-imag-ing, morbidity and mortality of the patients. R e s u l t s : The etiologies of seizures were remote symptomatic in 87 (54.3%), acute symptomatic in 38 (23.8%), progressive encephalopathy in 21 (13.1%), and idiopathic in 14 (8.8%). Status epilepticus occurred in 34 cases, including 8 cases of multifocal myoclonic status after hypoxic brain damage. The most common single cause of seizure was old stroke (35%, infarction in 41 and hemorrhage in 15 cases). Partial seizure was more common in patients with remote symptomatic than with other causes. Newly developed neurological deficits were present in 30 of the 151 who survived, including 15 acute symptomatic, 9 remote symptomatic, and 6 pro-gressive encephalopathy cases. Morbidity and mortality were highest in the acute symptomatic group (P<0.05) and tend to be low in the idiopathic group. Conclusions : We conclude that newly onset seizures in the elderly requiring hospitalization occur mainly with acute and remote symptomatic neurological insults. Acute symptomatic neurological insults are associated with a significant morbidity and mortality, while the morbidity is low in the absence of any asso-ciated neurological insults. J Korean Neurol Assoc 18(2):151~155, 2000 Key Words : Seizure, Elderly, Etiology Manuscript received November 17,1999. Accepted in final form December 30,1999. *Address for correspondence Hong-Ki Song, M.D. Department of Neurology, College of medicine,Hallym University, Gil-dong 445,Kangdong-ku,Seoul,134-701,Korea
Tel :+82-2-2224-2229 Fax :+82-2-487-6330 |
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