| 가족에서 발생한 Moyamoya질환:2례 보고 |
| 김상화, 강남제 김대성 정대수 박규현 최창화 |
| 부산대학교 의과대학 신경과학교실, 신경외과학교실* |
| Familial Occurrence of Moyamoya Disease:
Report of Two Families |
| Sang Hwa Kim, M.D., Nam Je Kang, M.D., Dae Seong Kim, M.D.,
Dae Soo Jeong, M.D., Kyu Hyun Park, M.D, Chang Hwa Choi, M.D.* |
| Department of Neurology and Neurosurgery*, Pusan National University,College of Medicine |
|
|
|
|
| Abstract |
|
Background : Whether the changes of risk factors (hypertension, diabetes mellitus, smoking, alcohol) can precipitate stroke remains unknown, and antecedent infection and psychologic stress are described insufficiently as predisposing risk factors for cerebral infarction. Therefore, we attempted to examine the roles of recent infection, psychologic stress, and the changes of risk factors as potential precipitants in each stroke subtypes. We also tested the temporal relationship between preceding exposure to coldness and stroke onset. Methods : In this case-control study, 113 consecutive patients with acute cerebrovascular disease (38 small vessel disease, 43 large vessel disease, 11 cardiogenic infarction, 4 infarction of undetermined cause, and 17 intracerebral hemorrhage) and 23 control subjects were evaluated. Changes of the risk factors (and their management) were interviewed. A sign/symptom based questionnaire was used to characterize the prevalence of recent prior infection and exposure to coldness. Psychologic stress was measured with the use of Social Readjustment Rating Scale. Results : The negative change of alcohol drinking was significantly higher in the stroke group. However, there was no significant difference between stroke and control groups in the changes of the other risk factors. The prevalence of previous (within 1 month) infection was significantly higher in the stroke group compared with control subjects (p=0.03). However, there were no significant differences among the stroke subtypes in the prevalence of infection(p=0.08). Upper respiratory tract infections constituted the most common type of infection. The exposure to coldness was significantly higher in the stroke group compared with control subjects (p=0.002). The level of stress within the prior 1 month/1 year was significantly higher in the stroke group than control group (p=0.01). Conclusion : Our data suggest that preceding infection, exposure to coldness, psychologic stress, and the negative change of alcohol drinking may be comm
Key Words : Stroke, Precipitants, Infection, Coldness, Stress |
|
PDF Links
Full text via DOI
Download Citation
