| 뇌혈류 및 신경언어학적 검사 방법을 이용한 피질하 실어증의 임상적 연구 |
| 박경원, 김재우, 박상호, 박지욱, 차재관, 김상우, 김덕규 |
| 동아대학교 의대 신경과. 핵의학과 |
| Clinical study of subcortical aphasia using brain SPECT and neurolinguistical methods |
| Kyoung Won Park, M.D., Jae Woo Kim, M.D., Sang Ho Kim, M.D., Ji Wook Park, M.D., Jae Kwan Cha, M.D., Sang Woo Kim, M.D., Duk Kyu Kim, M.D. |
| Department of Neurology, Department of Nuclear Medicine, College of Medicine, Dong-A University |
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| Abstract |
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Background & purpose : Subcortical aphasia is derived from infarction, hemorrhage or tumor in subcortical area, such as striatocpsular region, thalamus, paraventricualr white matter and corona radiata. To our knowledge, there have been few studies on subwrtical aphasia in Korea.
Objective : 1) To evaluate various lesion sites and clinical features associated with
subcortical aphasia. 2) To evaluate type and characteristics of subcortical aphasia by
Modified Western Aphasia Battery(MWAB) test. 3)To predict the mechanisms of
subcortical aphasia and to relate type of aphasia to hypoperfusion are a ascertained by
brain SPECT.
Methods : We analysed 19patients wing brain CT/MRI and neurolinguistical method of
MWAB, who presented language disturbance of aphasic nature due to subcortical
strokes. Cerebral blood flow was measured in 10 out of 19 patients using brain
SPECT.
Results & Conclusion : 1) The lesion sites responsible for subcortical aphasia were
caudate nucleus, putamen, internal capsule, thalamus, paraventricular white matter and
corona radiata. Hemiparesis and dysarthria were more common in subcortical aphasia
than in cortical one. 2) Subcortical aphasia was characterized by higher incidence of
anomic type and more rapid recovery than cortical aphasia. Most subcortical aphasia
following thalamic lesions revealed characteristic features of Preservation of repetition
and prominent deficits in naming. 3) Ten cases of subcortical aphasia showed both
cortical and subcortical hypoperfusion, suggesting that subcortical aphasia be derived
from secondary hypoperfusion of the cortical language area. In most of the patients, the
types and severity of subcortical aphasia correlated with the location and extent of
cortical hypoperfusion area. |
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