Cerebral vasospasm in eclampsia : report of a case

J Korean Neurol Assoc > Volume 15(2); 1997 > Article

Journal of the Korean Neurological Association 1997;15(2): 394-398.

뇌자기공명 혈관조영술로 혈관연축이 확인된 자간 1례

김병건, 이용석, 이한보, 박성호

서울대학교 의대 신경과, 서울특별시립보라매병원 신경과

Cerebral vasospasm in eclampsia : report of a case

Kim B K, M.D., Lee Y S, M.D., Lee H B, M.D., Park S H, M.D.

Department of Neurology, Seoul National University Hospital & Seoul City Boramae Hospital

Abstract

Background & Significance ; Eclampsia is defined by the concurrence of proteinuria, hypertension, convulsion and/or coma in the intrapartum or immediate postpartum period. Vasospasm of cerebral arteries is thought to be the basic pathophysiology of eciampsia. However there has yet been little direct evidence for vasospasm of cerebral arteries. Case : A 22-year old pregnant woman was admitted because of a labor pain and headache at the 40th week of gestation. She had no history of hypertension, seizure and migraine. On admission, hypertension and proteinuria were detected. She experienced a generalized tonic-clonic seizure and became comatose. Subarachnoid and intracranial hemorrage was excluded by cranial CT and lumbar puncture. Magnetic resonance angiography (MRA) on the 8th day after admission revealed diffuse vasospasm of cerebral arteries. Vasospasm disappeared on follow-up MRA performed 6 weeks later. Conclusion : Cerebral vasospasm was confirmed by MRA. In Korea, this is the first demonstration of reversible cerebral vasospasm in eclampsia.