A case of aseptic meningitis following intrathecal administration of methotrexate

J Korean Neurol Assoc > Volume 15(1); 1997 > Article

Journal of the Korean Neurological Association 1997;15(1): 233-236.

경막내 methotrexate 투여후 생긴 무균성 수막염 1예

도진국, 곽규호, 오희종, 이동국

대구 효성 가톨릭대학교 의대 신경과

A case of aseptic meningitis following intrathecal administration of methotrexate

Jin Kuk Do, M.D., Kyu Ho Kwak, M.D., Hee Jong Oh, M.D., Dong Kuck Lee, M.D.

Department of Neurology, School of Medicine, Catholic University of Taegu-Hyosung

Abstract

Methotrexate(MTX) is currently one of the most important antineoplastic drugs used in chemotherapy. Intrathecal(IT) MTX is widely used to treat or prevent meningeal leukemia and lymphoma. Aseptic meningitis following IT MTX is not uncommon, but not reported frequently in neurological field. We report a case of aseptic meningitis following IT MTX in acute lymphocytic leukemia.

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