Hemichorea-hemiballism with striatal high signal intensity on T1-weighted images in diabetes

J Korean Neurol Assoc > Volume 15(1); 1997 > Article

Journal of the Korean Neurological Association 1997;15(1): 128-136.

T1 강조 영상에서 선조체 고신호강도를 보이는 당뇨 환자에서의 편측무도증

정승철, 이병철, 김상윤, 배재천, 황성희, 도화범, 박종호

한림대학교 의대 신경과

Hemichorea-hemiballism with striatal high signal intensity on T1-weighted images in diabetes

Seung-Cheol Jeong,M.D., Byung-Chul Lee, M.D., Jae-Chun Bae, M.D., Sang-Yun Kim, M.D., Sung-Hee Hwang, M.D., Wha-Beom Doh, M.D., Jong-Ho Park, M.D.

Department of Neurology, Hallym University College of Medicine.

Abstract

Hemichorea-hemiballsim has been reported as a rare Implication of nonketotic hyperglycemia. Recently, Some reports revealed that brain magnetic resonance images of nonketotic hyperglycemic patients with hemichorea-hemiballism showed characteristic contralateral striatal signal abnormality, We present six patients with hemichorea-heniiballism. All of them had diabetes mellitus and performed brain MR images. The MR images of them showed high signal intensity on Tl-weighted images and low signal intensity on T2 weighted images in the striatum contralateal to the involuntary movement. In general, the striatal high signal intensity on TI weighted images are presumed to have developed following hemorrhagic transformation, osmotic myelinolysis, or mild ischemia with reversible deposition of calcium or other material occurred in association with nonketotic hyperglycemia. However the precise mechanism of this signal change is not clear yet and needs pathological confirmation.