Dysembryoplastic Neuroepithelial Tumor in Young Patients with Temporal Lobe Epilepsy

J Korean Neurol Assoc > Volume 14(2); 1996 > Article

Journal of the Korean Neurological Association 1996;14(2): 637-644.

측두엽간질환자에서 발견된 Dysembryoplastic Neuroepithelial Tumor

노숙영, 흥승봉, 서대원, 흥승철*, 서연림**

삼성의료원 신경과, 신경외과*, 병리과**

Dysembryoplastic Neuroepithelial Tumor in Young Patients with Temporal Lobe Epilepsy

Sook-Young Roh, M,D., Seung Bong Hong, M.D., Dae-Won Seo, M.D., Seung-Chyul Hong, M.D.*, Yeon-Lim Suh, M.D.**

Department of Neurology, neurosurgery*, and Pathology**, Samsung Medical center

Abstract

Three patients with complex partial seizures had dysembryoplastic neuroepithelial tumor (DNET) in temporal lobe. In all cases, longterm video-EEG monitoring showed epileptogenic focus in left temporal lobe where small mass lesion was located. For further seizure localization and functional mapping, subdural grids were placed on left temporal lobe including lesions. Lateral temporal lobectomy with lesionectomy was performed in two cases. Lateral temporal lobe resection and amygdalohippocampectomy was done in one case. The pathological findings of all lesions were characterized by intracortical location, multiple nodular architecture, foci of dysplastic cortical disorganization and the presence of a specific glioneuronal element. All patients have been seizure free.