A Case of Diffuse Leukoencephalopathy Caused by 5-Fluorouracil

J Korean Neurol Assoc > Volume 13(4); 1995 > Article

Journal of the Korean Neurological Association 1995;13(4): 1007-1010.

5-FU에 의한 미만성 백질 뇌병증 1례

박유미, 권혜영, 김후원, 김동권

대전 을지병원 신경과

A Case of Diffuse Leukoencephalopathy Caused by 5-Fluorouracil

Yoo Mi Park, M.D., Hye Young Kwon, M.D., Hoo Won Kim, M.D., Dong Kwon Kim, M.D

Department of Neurology, Taejon, Eulji Hospital

Abstract

5-Fluorouracil is one of the most commonly used anticancer drug. We report a case of leukoencephalopathy who had received 5-fluorouracil injection following operation of carcinoid tumor in intestine. The case had dementia, dysarthria and gait disturbance. Brain CT showed bilaterally symmetric diffuse low densities in the white matter of cerebrum and cytologic examination of cerebrospinal fluid was negative for malignancy. Discontinuation of 5- fluorouracil injection for several days and then improved the clinical symptoms.

TOOLS

PDF Links
Full text via DOI
Download Citation
Share :

METRICS

1,516 View
8 Download

Related articles

Reversible Leukoencephlaopathy Caused by Doxifluridine in a Patient with Gastric Cancer2016 February;34(1)

A Case of Transient Hemolysis Caused by Midazolam2011 ;29(4)

A Case of Bilateral Sciatic Neuropathy Caused by Lotus Position2004 ;22(4)

"A Case of Post-Transfusion Posterior Leukoencephalopathy with Cytotoxic and Vasogenic Edema" 2003 ;21(1)

A Case of Reversible Posterior Leukoencephalopathy After Rhabdomyolysis2001 ;19(2)

Editorial Office: (ZIP 03163) #1111, Daeil Bldg, 12, Insadong-gil, Jongno-gu, Seoul, Korea
Tel: +82-2-737-6530 Fax: +82-2-737-6531 E-mail: jkna@neuro.or.kr