A Case ot Acute sensory neuronopathy

J Korean Neurol Assoc > Volume 13(1); 1995 > Article

Journal of the Korean Neurological Association 1995;13(1): 158-163.

급성 감각신경원병증 (Acute sensory neuronopathy) 1례

서병현, 조수현, 최문성, 박기현

메리놀병원 신경과, 부산대학교 신경과

A Case ot Acute sensory neuronopathy

Byeong Hyun Suh, M.D., Su Hyun Cho, M.D., Mun Seong Choi, M.D., Kyu Hyun Park, M.D.

Department of Neurology, Maryknoll General Hospital, and Pusan National University Hospital

Abstract

We have had an opportunity to study a patient with acute sensory neuronopathy. The patient was a 32-yearold housewife; the rapidly spreaded tingling sensation along both arms and legs developed, rendering her severely ataxic. There was no history of antecedent illness, familial neurological disease, or exposure to toxins and special drugs. On examinations, there was no abnormality in her mental and cranial nerve function. There was no motor weakness. She showed the profound loss of kinesthetic sense which was acutely progressive and associated with severe sensory ataxia and pseudoathetosis. All tendon reflexes were absent. However, cutaneous senses were preserved. There was no significant abnormal laboratory finding except elevated CSF protein content. On electrophysiologic findings, the decrease in the amplitude of action potentials with only mild slowing of conduction velocities of sensory nerves were found even though motor nerve conduction studies were normal. Median and tibial somatosensory evoked potentials could be elicited, although the median N19 scalp response and tibial N45 waveforms were prolonged in latency. Plasmapheresis were provided; clinical features improved. However, the electrophy-siological abnormalites remained. Thus we wish to report an additional case of woman suffering from the acute sensory neuronopathy, complementing the cases described by Stemm, Schaumburg and Asbury. Key Words: Acute sensory neuronopathy, Electrophysiologic studies, A case