A Case of Neuroleptic Malignant Syndrome associated with ?Choreoballism due to the Delayed Complication of Carbon Monoxide ?Intoxication

J Korean Neurol Assoc > Volume 12(3); 1994 > Article

Journal of the Korean Neurological Association 1994;12(3): 556-559.

연탄가스중독의 후유증으로 발병한 무도성발리즘에 동반된 신경이완제? 악성증후군 1례

김종열, 김지은,정보우,서청규

경북대학교 신경과.

A Case of Neuroleptic Malignant Syndrome associated with ?Choreoballism due to the Delayed Complication of Carbon Monoxide ?Intoxication

Jong Yeol Kim, M.D., Ji Eun Kim, M.D., Bo Woo Jung, M.D., Chung Kyu Suh, M.D.

Department of Neurology, School of Medicine, Kyungpook National University Taegu, Korea

Abstract

Neurologic complications such as mental status changes, incontinence, gait disturbances, extrapyramidal symptoms may be delayed days or weeks after exposure to carbon monoxide but hyperkinesia such as choreoballism and athetosis rarely occurs as symptoms of delayed neurologic complication of carbon monoxide intoxication. Neuroleptic malignant syandrome (NMS) is a rare, potentially fatal drug-induced disorder associated with hyperthermia, muscle rigidity, autonomic instability, mental dysfunction and various dyskinesia. Various major neuroleptic drugs seem to be its culprits. We describe a 24-year-old female patient who presented with NMS following administration of haloperidol for choreoballism, a symptom of delayed neurologic sequelas after carbon monoxide intoxication, with a review of the literature.