Radiation-Induced Lumbosacral Plexopathy : Clinical and ?Electrophysiological Findings in 3 Cases

J Korean Neurol Assoc > Volume 12(1); 1994 > Article

Journal of the Korean Neurological Association 1994;12(1): 152-158.

방사선 요천추 신경총병증 3예

이상암, 김광국,이명종

울산대학교 신경과. 서울중앙병원 신경과.

Radiation-Induced Lumbosacral Plexopathy : Clinical and ?Electrophysiological Findings in 3 Cases

Sang Ahm Lee, M.D., Kwang Kuk Kim, M.D., Myoung Chong Lee, M.D.

Department of Neurology, College of Medicine , University of Ulsan

Abstract

Radiation-induced neuropathy is a rare but well recognized clinical entity although peripheral nerves are considered to be relatively resistant to irradiation. We report three patients with radiation-induced lumbosacral plexopathy, whose characteristic clinical and electrophysiological features can be summarized as follows: 1) 55-58 year old women who were previously treated with radiotherapy for uterine cervix carcinoma: 2) the latent period is to 10 from 13 years: 3)predominantly motor involvement with slowly progressive paraparesis, asymmetrical onset and worse in distal muscle group: 4) painless at onset, with variable degree of sensorv changes: 5)decreased or absent knee and ankle jerks :6)axonal damage in electrophysiologic study: 7)frequent myokymic discharges. Myokymic discharges occur in bursts at regular rate of 0.1 to 8 Hz. In myokymic bursts with more spikes, interburst interval is longer but interspike Interval is shorter