A Case of Remitted Lambert-Eaton Myasthenic Syndrome with Small Cell Lung Carcinoma Following Chemotherapy and Radiotherapy

J Korean Neurol Assoc > Volume 10(3); 1992 > Article

Journal of the Korean Neurological Association 1992;10(3): 401-406.

화학요법과 방사선치료로 완전 관해된 폐소세포암을 동반한 Lambert-Eaton Myasthenic Syndrome 1예

이상암, 선우일남,노재경,박기덕

연세대학교 신경과, 내과. 이화여자대학교 내과, 신경과.

A Case of Remitted Lambert-Eaton Myasthenic Syndrome with Small Cell Lung Carcinoma Following Chemotherapy and Radiotherapy

Sang-Ahm Lee, M.D., Il-Nam Sunwoo, M.D., Jae-Kyoung Ro, M.D., Kee-Duk Park, M.D.

Department of Neurology and Internal Medicine, College of Medicine, Yoensei University, Department of Neurology and Internal Medicine, College of Medicine, Ehwa Womans University

Abstract

In one case of cancer-associated Lambert-Eaton myasthenic syndrome (LEMS), treatment with cytotoxic chemotherapy and radiotherapy resulted in remission of both cancer and neuromuscular disorder. Serial repetitive nerve stimulation (RNS) findings showed that the typical RNS features of LEMS returned to normal in the orders of dramatic postexercise facilitation, an incremental response in high rate stimulation, and a decremental response in low rate stimulation with clinical improvement.