A Case of Extrapontine Myelinolysis Without Central Pontine Myelinolysis Following Hyponatremia

J Korean Neurol Assoc > Volume 10(3); 1992 > Article

Journal of the Korean Neurological Association 1992;10(3): 375-381.

중심뇌교 침범없이 나타난 뇌교외 수초용해증 1례

조경원, 나정균,정원영,조기현,김세종

조선대학교 신경과. 전남대학교 신경과.

A Case of Extrapontine Myelinolysis Without Central Pontine Myelinolysis Following Hyponatremia

Kyung-Won Cho, M.D., Jung-Gyun Na, M.D., Won-Young Jung, M.D., Ki-Hyun Cho, M.D., Sei-Jong Kim, M.D

Department of Neurology, College of Medicine, Chosun Universtiy, Department of Neurology, College of Medicine, Chonnam National University

Abstract

Central pontine myelinolysis (CPM) is characterized by regions of demyelination throughout the brain but most prominent in the pons. The symptoms of CPM include rapidly evolving quadriplegia, pseudobulbar palsy and varying degree of altered consciousness. The exact pathogenesis is unknown. We report a rare case of extrapontine myelinolysis (EPM) without CPM; A 49-year-old man with chronic alcoholism and chronic type B hepatitis were presented with clinical symptoms of rapidly progressive quadriplegia and pseudobulbar palsy preeded by hyponatremia. Magnetic resonance imaging in this patient showed bilateral increased T2-weighted signals in the caudate nucleus and the putamen.