A Case of Acute Paraplegia in Hypereosinophilic Syndrome

J Korean Neurol Assoc > Volume 9(3); 1991 > Article

Journal of the Korean Neurological Association 1991;9(3): 380-385.

호산구증가 증후군 환자에서의 급성 하반신마비 1례

유경무, 박영춘

고신대학교 내과. 계명대학교 신경과.

A Case of Acute Paraplegia in Hypereosinophilic Syndrome

Kyung Mu Yoo, M.D. Young Choon Park, M.D.

Dep. Of Internal Medicine, Kosin Medical College Dep. Of Neurology, Keimyung University School of Medicine

Abstract

Hypereosinophilic syndrome (HES) is characterized by a persistent eosinophilia of l,500/mm3 lasting for at least 6 months associated with multi-system involvement and no other identifiable cause. A 45-year-old man had hypereosinophilia, cardiopathy, and acute paraplegia. Following corticosteriod with antipletelet agent therapy, paraplegia was improved rapidly and circulating eosinophils were normalized. We postulated that embolic phenomenon was due to hypercoagulable state by eosinophil-derived proteins and/or to direct infiltration by eosinophils.