Studies on Visual Evoked Potentials in Parkinson's Disease

J Korean Neurol Assoc > Volume 4(2); 1986 > Article

Journal of the Korean Neurological Association 1986;4(2): 179-184.

파킨슨씨 질환에서의 시각 유발전위 (VEP)에 관한 연구

이광우, 명호진

서울대학교 신경과.

Studies on Visual Evoked Potentials in Parkinson's Disease

Kwang-Woo Lee, M.D., Ho-Jin Myung, M.D.

Department of Neurology, College of Medicine, Seoul National University

Abstract

Checkerboard pattern reversal visual evoked potentials were studied in 18 patients with Parkinson's disease and in 20 normal controls without ocular diseases. 1. The interocular differences of Pl latencies and Nl-Pl amplitudes were significantly larger in the Parkinsonian group than in the normal control. 2. The absolute Pl latency was longer and the absolute Nl-Pl amplitude was smaller in the Parkinsonism group before dopaminergic therapy than in the normal control. 3. The absolute Pl latency was also longer in the Parkinsonian group after a peiod of levodopa treatment than in the normal control, but there was no significant difference of absolute Nl-Pl latency between them. From these findings, authors confirmed the suggestion that at least part of the delay of the Pl latency occurs at prechiasmal level of the visual system in Parkinson's desease.