A Cases of Familial Spastic Paraplegia (FSP)

J Korean Neurol Assoc > Volume 3(2); 1985 > Article

Journal of the Korean Neurological Association 1985;3(2): 2091-297.

가족성 경성 대마비 1례

하정상, 서보완, 변영주, 박충서, 최원희

영남대학교 신경과, 해부병리학.

A Cases of Familial Spastic Paraplegia (FSP)

Jung-Sang Ha,M.D.,Won-Hee Choi, M.D., Choong-Seo Park, M.D., Yung-Joo Byun, M.D., Bo-Wan Seo, M.D.

Department of Neurology, Pathology, Yungnam University

Abstract

We present a family of FSP with review of literatures. Seeligmuller (1876) and Strumpell (1880) were the first to describe familial case of spastic paraplegia characterized by progressive weakness and spasticity of the lower limbs with little or no involvement of the upper extremities. This syndrome is heterogenous in inheritance, age of onset, severity and associated signs. A pure type without complications has been named ""Strumpell's FSP."" We have recently experienced a case of 17 years old male who had bilateral weakness and stiffness of lower extremities, and gait disturbance with family history. Differential diagnosis, particularly with familial amyotrophic lateral sclerosis, is discussed.