Hemagglutination Inhibition Test in Epidemic Encephalitis of Korea

J Korean Neurol Assoc > Volume 3(2); 1985 > Article

Journal of the Korean Neurological Association 1985;3(2): 203-209.

하기유행성 뇌염에서의 일본뇌염 혈구응집저지 반응 검사

선우일남, 김기환

연세대학교 신경과.

Hemagglutination Inhibition Test in Epidemic Encephalitis of Korea

Il-Nam Sun-Woo, M.D.,Ki-Hwan Kim, M.D.

Department of Neurology, Yunse University

Abstract

Analyzing HI tests of 110 cases of clinical Japanese Encephalitis in 1982, the following results are obtained. 1. The results of HI test are positive in 39 (35.5%), borderline positive in 19 (9.1%), negative in 14 (12.7%) and undetermined in 47 (43.7%) cases. 2. In 49 cases of positive HI test, 14 cases reveal the positive result on the first HI test requested in 5-27 days after the clinical onset of symptoms, and 35 cases show increasing HI titers on the follow-up studies. There is a tendency of increasing HI titers upto 3-4 weeks of onset and sustaining the value for more than two months. 3. In 35 cases with increasing titers on follow-up study, the highest titer is 1:80 in 5 cases, and the half of HI negative cases maintain that value throughout the course. 4. There is no significant statistical differences in clinical characteristics, laboratory and cerebrospinal fluid studies between the patient group of HI positive or borderline and group of HI negative or undermined, except mean hospital day and incidence of coma and death.