A Case of Pernicious Anemia with Neurologic Involvement

J Korean Neurol Assoc > Volume 2(2); 1984 > Article

Journal of the Korean Neurological Association 1984;2(2): 181-187.

신경계 증상을 동반한 악성빈혈 1예

황연미, 선우일남, 김기환 , 고윤웅

연세대학교 신경과, 내과.

A Case of Pernicious Anemia with Neurologic Involvement

Yeon-Mi Hwang, M.D., Il-Nam Seonwoo, M.D., Ki-Hwan Kim, M.D., Yun-Woong Koh, M.D.

Department of Neurology, and Internal Medicine College of Medicine Yeonsei University

Abstract

This is a case report of pernicious anemia with neurologic deficits. The patient is a 69 years old male with generalized tingling sense. On examination, slight pale conjunctiva and beefy red tongue are noted. Laboratory stud show megaloblastic anemia with low serum vitamin B12 level, positive Schilling test, gastric achlorhydria and mild gastric atrophy. Neurologic examination reveals cerebral, spinal and peripheral involovement and EEG and EMG study support those things. On parenteral vitamin B12, the hematologic and neurological abnormalities are improved dramatically.