Focal Seizure Disorder with Spontaneous Regression of ?Epileptogenic Lesion on Serial Computed Tomography

J Korean Neurol Assoc > Volume 2(2); 1984 > Article

Journal of the Korean Neurological Association 1984;2(2): 132-140.

일련의 전산화단층촬영상 간질유발성 병변이 자연적으로 퇴화되는 ?국소성 경련성 질환

이광호, 명호진

서울대학교 신경과.

Focal Seizure Disorder with Spontaneous Regression of ?Epileptogenic Lesion on Serial Computed Tomography

Kwang-Ho Lee, M.D., Ho-Jin Myong, M.D.

Department of Neurology, Seoul National University

Abstract

During a period of four years the authors experienced eighteen cases of focal seizure disorder, showing small ring or nodular enhancement with surrouding low density on CT scans. In fifteen cases, the epileptogenic lesions decreased in size or resolved completely on serial CT scans. Three cases were explored surgically. Males and famales were equally affected. Their age ranged from six to fourtyfive years and fifteen patients were under the age of thirty years. The principal symptoms and signs consisted of focal siezures (17 cases), generalized seizure during sleep (1 case), focal neurological deficits (14 cases), and intracranial hypertension (4 cases). The lesions of CT scans were found frequently in the parietal and frontal lobes. The clinical course of this self-limited disorder was variable and well correlated with the change of CT findings. The histological findings were the typical tuberculoma and the caseating gramuloma containing calcium in two cases. In one case the enhancing nodule of CT scan was not resected and the tissue specimen around the nodule revealed nonspecific inflammation. The cause of this disorder might be tuberculoma, but in some cases we could not rule out cysticercosis.