| 측두엽 간질환자에서 수술 후 지속되는 전조에 관련된
요인에 관한 비교 |
| 곽규환, 강중구·마효일·이상암·최충곤*·이정교** |
| 울산대학교 의과대학 서울중앙병원 신경과, 진단방사선과*, 신경외과** |
| Comparison of factors related to persistent aura in TLE patients after temporal lobectomy |
| Kyu-Hwan Kwak, Joong-Koo Kang, Hyeo-Il Ma, Sang-Ahm Lee, Choong-Gon Choi*, Jung Kyo Lee** |
| Department of Neurology, Neuroradiology*, Neurosurgery**, Asan Medical Center,
Ulsan University Medical College |
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| Abstract |
Background: Persistent auras after temporal lobectomy may be bothersome to the patients even though they are seizure free. But most authors specifically are concerned about the seizure outcome itself. The aim of the present study was to investigate which factors are related to persistent auras in patients with temporal lobe epilepsy(TLE) after temporal lobectomy.
Methods: We have retrospectively analysed many factors in 38 TLE patients with aura. All patients underwent anterior temporal lobectomy with amygdalo-hippocampectomy. Twenty three patients were seizure and aura free (completely seizure-free) and 15 patients had persistent auras(persistent auras) in spite of seizure-free. Characteristics of auras, past medical history, presence of secondary GTC, seizure frequency, age of surgery, age of onset, duration of habitual seizure, ictal EEG pattern, and pre- and postoperative MRI findings were compared between group with completely seizure-free and group with persistent aura.
Results: Characteristics of aura, past medical history, presence of secondary GTC, seizure frequency, ictal EEG pattern, age of onset, and age of surgery had no statistical differences between both groups. Seizure duration of group with persistent aura seemed to be longer than that of group with completely seizure-free(13.6 years vs 17.0 years, median test, p=0.10) and remained hippocampus in postsurgical MRI seemed to be related to persistent auras(Fisher's exact test, p=0.06).
Conclusions: We found that there were suggestive differences in seizure duration and remained hippocampus between the two groups.
Key Words : temporal lobe epilepsy, prognosis, aura, hippocampal sclerosis |
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