| 정상성인 200명을 대상으로한 Transcranial Doppler Ultrasonography ?(TCD)의 기준치와 그에 영향을 주는 요소들 |
| 김경환, 손영호, 이상무, 이준홍, 김돈수, 김정연, 김진수 |
| 연세대학교 신경과 및 뇌연구소 |
| The Reference Values and Influencing Factors of TCD Measurements ?in 200 Normal Korean Adults
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| Gyung Whan Kim, M.D., Young Ho Sohn, M.D., Joon Hong Lee, M.D., Doo Soo Kim, M.D., Jeong Yeon Kim, M.D., Jin Soo Kim, M.D. |
| Department of Neurology and Institute of Brain Research, Yonsei University, College of Medicine |
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| Abstract |
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The clinical utility of transcranial doppler ultrasonography (TCD) in cerebrovascular disease has been extended recently. Although number of studies have been performed to define normal reference values of TCD measurements, they have some limitations to be used as reference values which include relatively small number of subjects, lack of data about some cerebral vessels and/or parameters. This study was aimed to obtain clinically useful reference values of TCD measurements with consideration of the influence of age and sex in Korean adults, particularly who are in stroke-prone age group. We measured flow velocities, pulsatility indecies, side-to-side differences and vasomotor reactivities of all intra-and extracranial cerebral arteries using TCD in 209 normal Korean adults (age, 23-78 years; 94 men and 115 women), and analyzed the influence of age and sex on those measurements. With advancing age, subjects showed significant reduction in velocity measurements and increase in pulsatility indecies of most examined arteries. Females showed hight velocities of middle cerebral, internal carotid, vertebral and basilar artery and lower pulsatility indecies of middle cerebral arteries compared with males. Asymmetry measurements including side-to-side differences and asymmetry index, and ,breath holding index testing vasomotor reactivity were also measured and the normal range of those parameters were calculated. Since present study included large number of subjects, and checked paramenters of TCD in both extra- as well as intracranial cerebral arteries, we are convinced that these results can be used as a reference data of TCD measurements in Korean adults.
Key Words : Transcranial doppler ultrasonography, Cerebral artery, Cerebral blood flow,
Pulsatility Index, Vasomotor reactivity |
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