Pisa Syndrome in a Patient with Alzheimer’s Disease and Concomitant Normal Pressure Hydrocephalus: A Case Report

J Korean Neurol Assoc > Volume 26(1); 2008 > Article

Journal of the Korean Neurological Association 2008;26(1): 73-77.

알츠하이머병에서 동시에 증상이 나타난 Pisa 증후군과 정상압 수두증

대구가톨릭대학교 의과대학 신경과학교실

Pisa Syndrome in a Patient with Alzheimer’s Disease and Concomitant Normal Pressure Hydrocephalus: A Case Report

Oh Dae Kwon

Department of Neurology, School of Medicine, Catholic University of Daegu, Daegu, Korea

Abstract

Extrapyramidal symptoms are common in patients with advanced Alzheimer’s disease and have various etiologies. We report a 65-year-old man with probable Alzheimer’s disease (AD) who concomitantly developed Pisa syndrome, ataxic gait, postural instability and voiding difficulty. Pisa syndrome improved after the discontinuation of acetylcholinesterase inhibitor (AchEI) and antipsychotics. However his ataxic gait and voiding symptoms persisted. A ventriculo-peritoneal shunt operation eliminated the symptoms except for cognition. We report Pisa syndrome in a patient with Alzheimer’s disease and concomitant normal pressure hydrocephalus.KeyWords:Alzheimer disease, Normal pressure hydrocephalus, Pisa syndrome