Different Lesion Patterns in Cerebral Infarction Associated with
Hypereosinophilic Syndrome

J Korean Neurol Assoc > Volume 30(1); 2012 > Article

Journal of the Korean Neurological Association 2012;30(1): 45-48.

과다호산구증후군과 연관된 뇌경색 병변의 양상

조경희, 손성일

계명대학교 의과대학 신경과학교실 a , 고려대학교 의과대학 신경과학교실 b

Different Lesion Patterns in Cerebral Infarction Associated with Hypereosinophilic Syndrome

Kyung-Hee Cho

Department of Neurology , Keimyung University School of Medicine, Daegu, Korea Department of Neurology b , Korea University College of Medicine, Seoul, Korea

Abstract

Hypereosinophilic syndrome is a rare disorder that can cause ischemic stroke. We report two patients with cerebral infarction due to hypereosinophilic syndrome. Brain MRI of each patient revealed different lesion patterns of cerebral infarcts, which included multiple border-zone infarcts and a small perforating-artery infarct. The mechanism underlying the small infarct in one of the patients was presumed to be vascular endothelial toxicity by eosinophilic cells and local thrombus formation, and the distinguishing lesion pattern of this patient has not been reported previously. Key Words: Hypereosinophilia, Ischemic stroke, Magnetic resonance imaging