2 cases of plasma cell granulomas involving intracranium

J Korean Neurol Assoc > Volume 17(3); 1999 > Article

Journal of the Korean Neurological Association 1999;17(3): 435-441.

두개내에 발생한 형질세포육아종(Plasma Cell Granuloma) 2예

천대웅, 주성민, 김후원, 김병기, 안병철, 오건세, 양기화

을지 의과대학 신경과학교실, 병리학교실

2 cases of plasma cell granulomas involving intracranium

Dae-Woong Tchun, M.D., Seong-Min Ju M.D., Hoo-Won Kim, M.D., Byung-Gi Kim, M.D., Byung-Chul Ahn, M.D.,Gun-Sei Oh, M.D., Gi-Hwa Yang*, M.D.

Department of Neurology, Eulji Medical College, #24, Mok-dong, Joong-ku, Taejon, 301-070,

Abstract

Plasma cell Granuloma (PCG) is a form of idiopathic inflammatory pseudotumor (IPT). It is a rare entity character-ized by a nonneoplastic proliferation of inflammatory cells dominated by a polyclonal expansion of the plasma cells. This lesion has been discovered in many parts of the body including the central nervous system. We now report two cases of plasma cell granuloma involving the brain. The first case was a 42-year-old man who presented a right hemi-paresis. He had a lesion in the convexity of the left parietal region. The second case was a 58-year-old woman who was expressed confusion and a frontal-temporal headache. She had a lesion in the convexity of the left temporal region and mastoid bone. The diagnosis of PCG was confirmed by pathological and immunohistochemical studies revealing pre-dominant plasma cells in the affected tissues. 두개내에 발생한 형질세포육아종 (Plasma Cell Granuloma)2예 J Kor Neurol Ass 17(3):435 ~ 441, 1999 Gun Sei Oh, M.D. Key Words : Plasma cell granuloma, Inflammatory pseudotumor, Central nervous system