Multiple Germ Cell Tumors Manifesting as Anterior Hypothalamic and Pretectal Syndromes

J Korean Neurol Assoc > Volume 23(2); 2005 > Article

Journal of the Korean Neurological Association 2005;23(2): 264-267.

앞시상하부와 덮개앞증후군으로 발현한 다중배아세포종양

문소영, 박성호 황정민* 박민수† 김지수

서울대학교 의과대학 신경과학교실, 안과학교실*, 국군수도병원 신경과

Multiple Germ Cell Tumors Manifesting as Anterior Hypothalamic and Pretectal Syndromes

So Young Moon

Departments of Neurology and Ophthalmology*, Seoul National University College of Medicine, Seoul; Department of Neurology, Armed Forces Capital Hospital†, Seongnam, Korea

Abstract

A 21-year-old man presented with vertical diplopia and subsequently developed heat-dissipation deficit, central diabetes insipidus, light-near dissociation of the pupillary responses, convergence-retraction nystagmus, and mild upgaze limitation. These were consistent with the anterior hypothalamic and pretectal syndromes. Gadolinum- enhanced MRI revealed lesions, involving the suprasellar and pretectal areas, which were consistent with multiple germ cell tumors. The rare combination of anterior hypothalamic and pretectal syndromes may be manifestation of multiple germ cell tumors and require careful evaluation of these areas using gadolinum- enhanced MRI. KeyWords:Suprasellar, Pretectal syndrome, Germ cell tumor