Anti-GM1 Antibody Associated Acute Motor Conduction Block
Neuropathy Presenting With Reversible Conduction Failure

J Korean Neurol Assoc > Volume 31(4); 2013 > Article

Journal of the Korean Neurological Association 2013;31(4): 254-257.

가역전도장애를 보이는 항-GM1항체연관 급성 운동전도차단신경병

김현우, 박영은 a,b 김종국 c 박규현 a,b 김대성 a,b

부산대학교 의학전문대학원 신경과학교실 a , 부산대학교병원 의생명연구원 b , 동아대학교 의과대학 신경과학교실 c

Anti-GM1 Antibody Associated Acute Motor Conduction Block Neuropathy Presenting With Reversible Conduction Failure

Hyun-Woo Kim

Department of Neurology a , Pusan National University School of Medicine, Busan, Korea Biomedical Research Institute b , Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea Department of Neurology c , Dong-A University College of Medicine, Busan, Korea

Abstract

A 57-year-old man developed motor weakness and paresthesia after acute enteritis. Nerve conduction study revealed decreased compound muscle action potentials in median nerves and conduction blocks in ulnar nerves. Serum IgG anti-GM1 antibody was positive. Conduction blocks rapidly disappeared through sequential studies, which are defined as reversible conduction failure (RCF). This study represents anti-GM1 antibody-associated acute motor conduction block neuropathy based on RCF. We underline that serial nerve conduction studies might be required for characterization of clinical and electrophysiological features. Key Words: Reversible conduction failure, Acute motor conduction block neuropathy, Anti-GM1 antibody