Quality of Life in Patients with Parkinson s Disease

J Korean Neurol Assoc > Volume 20(3); 2002 > Article

Journal of the Korean Neurological Association 2002;20(3): 227-233.

파킨슨병 환자의 삶의 질

홍석경 , 홍석경 박경원경 차재관 김상호 천동렬 양창국 김재우

동아대학교 의과대학 신경과학교실,정신과학교실

Quality of Life in Patients with Parkinson s Disease

Seuk Kyung Hong, M.D.

Department of Neurology and Psychiatry*, College of Medicine, Dong-A University

Abstract

"Background : Quality of life (QoL) has emerged as an important issue to patients with chronic illness. Parkinson s disease (PD) is a chronic neurodegenerative disorder requiring life-time treatment and supportive care, which affects not only physical activity but also cognition, mood, and daily living. The author investigated the QoL of patients with PD and aimed to find factors that have an influence on the QoL. Methods : One hundred thirty patients with PD were evaluated. The QoL was measured and assessed by the Parkinson s disease quality of life questionnaire (PDQL). The author analyzed demographic and social data and clinical profiles. The Beck Depression Inventory (BDI) and Spielburger s State-Trait Anxiety Inventory were used to evaluate depressive symptoms and anxiety levels. Results : The mean age of onset of parkinsonian symptom was 55.2 ±10.9 years and the average duration of treatment was 34.7 ±36.9 months. Patients with high BDI score, low Schwab and England activities of daily living scale (SEADLS) score, high bradykinesia score, progressed Hoehn and Yahr stage, high Unified Parkinson s disease rating scale score, low educational period and high economic state were all correlated with low PDQL scores. Multivariate regression analysis showed that BDI score, bradykinesia score, SEADLS score, and educational period were significantly associated with PDQL score. Conclusions : In order of magnitude, BDI, bradykinesia, SEADLS and educational period were influenc-ing factors on PDQL. Therefore, to improve the QoL in patients with PD, we should consider not only physical disabili-ty, but also psychological factors, including depressive mood.Key Words : Parkinson s disease, Quality of life, Parkinson s disease quality of life questionnaire, Depression"