Cerebral infarction : Diagnosis and Assessment of
Prognosis by TC-HMPAO & TC-DTPA brain SPECT

J Korean Neurol Assoc > Volume 13(2); 1995 > Article

Journal of the Korean Neurological Association 1995;13(2): 187-193.

뇌 단일양전자방출 단층촬영에 의한 뇌경색의 진단 및 예후 추정

손준호, 박상준, 김두천, 김요식, 김명규, 조기현, 김세종, 범희성

전남대학교 신경과

Cerebral infarction : Diagnosis and Assessment of Prognosis by TC-HMPAO & TC-DTPA brain SPECT

Joon Ho Son, M.D., Sang Joon Park, M.D., Du Cheun Kim, M.D., Yo Sik Kim, M.D., Myung Gyu Kim, M.D., Ki Hyun Cho, M.D., Sei Joing Kim, M.D., Hee Seung Beum, M.D.

Department of Neurology and Department of Neclear Medicine, Chonnam National University Hospital

Abstract

To evaluate the usefulness of brain SPECT as a tool with diagnostic and prognostic values m patients with acute cerebral infarction, twenty-four patients who were diagnosed as embolic(n=12) or thrombotic(n7-12) infarction by clinical manifestation and brain CT or MRI were selected. Both 99mTc-HMPAO & 99mTc-DTPA Brain SPECT were performed for each patients within 1 week after the attack Asymmetric index(Al) in both hemispheres was calculated as 200(l(right-left)l/(right+left)). Activities of daily livmg(ADL) was scored by Barthel Index on the admission day and the 21st day after the attack. The relationshiop between ADL index and Al of two types of brain SPECT was analysed by calculating correlation coefficient. 1.In embolic infarction, the Al of 99mTc-DTPA SPECT was markedly higher than that of 99mTc-HMPAO spect, but there was no difference in thrombotic type. 2. The AI of 99m'Tc-DTPA SPECT in embohc infarction was sigiuficantly higher than that m thrombotic type(p valu=.001), but the Al of 99mTc-HMPAO SPECT was similar in both types of infarction. 3.The correlation coefficient Al of 99mTc-DTPA Brain SPECT and ADL m the 21st day after stroke was statistically significated. These results suggested that the 99mTc-DTPA brain SPECT should be useful not only for the differemtial diagnosis between thrombotic and embolic infarctions but also for the prediction of prognosis in patients with ischemic stroke.