Oligoclonal Bands in Cerebrospinal fluid of Neurologic patients

J Korean Neurol Assoc > Volume 2(2); 1984 > Article

Journal of the Korean Neurological Association 1984;2(2): 149-154.

신경계 환자의 뇌척수액에서의 Oligoclonal Bands의 관찰

권오상, 명호진

서울대학교 신경과.

Oligoclonal Bands in Cerebrospinal fluid of Neurologic patients

Oh-Sang Kwon, M.D., Ho-Jin Myong, M.D.

Department of Neurology, Seoul National University

Abstract

The authors studied the diagnostic value of the oligoclonal band in cerebrospinal fluid in various neurological disorders. Cerebrospinal fluid of thirty-one patients including eight cases of multiple sclerosis was tested for oligoclonal band by agarose gel electrophoresis using the Helena Titan Gel High Resolution Protein System. Oligoclonal bands were detected in eleven cases of various disorders (two cases of optic neuritis, three cases of multiple sclerosis, three cases of CNS cysticercosis, and three cases of other disorders). This study suggested that detection of oligoclonal band in CSF was of usdful diagnostic aid in multiple sclerosis in addition to CSF IgG/Albumin ratio and CSF IgG index.