| 크로이츠펠트-야콥씨 병 |
| 권오현, 나덕렬, 이정일, 서연림, 서대원, 김상은, 위봉애 |
| 삼성의료원 신경과. 신경외과. 해부병리학과. 핵의학과, 서울대학교 신경과, 노원 을지병원 |
| Creutzfeldt-jakob disease |
| O Hyoun Kwon, M.D., Duk L. Na, M.D., Jung Il Lee, M.D., Yeon-Lim Suh, M.D., Dae Won Seo, M.D., Sang Eun Kim, M.D., Bong Ae Wie, M.D. |
| Department of Neurology, Neurosurgery, Diagnostic Pathology, Nuclear Medicine, Samsung Medical Center, Department of Neurology, Seoul National University, Department of Neurology, Eul Ji Medical Center |
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| Abstract |
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We present three neuropathologically-verified and two clinically-probable cases of Creutfeldt Jakob disease. All five had nonspecific prodromal complaints or symptoms prior to overt neurological signs and showed striking progressive neurologic deterioration, especially cognitive decline and cerebellar dysfunction. Myoclonic involuntary movements and complete decapitated states followed in one or two months. The characteristic even pathognomonic in proper clinical settings, features of electroencephalography, magnetic resonance imaging and positron emission tomography and pathologic findings are presented. |
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