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Journal of the Korean Neurological Association 2014;32(1): 22-25.
안면상완근긴장발작으로 발현한 항LGI1항체 자가면역뇌염
김현진, 김보미 황지혜 이유진 이순태
울산대학교 의과대학 신경과학교실, 서울대학교 의과대학 신경과학교실
Anti-LGI1 Antibody Autoimmune Encephalitis Which Manifests Faciobrachial Dystonic Seizure
Hyunjin Kim
Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Neurology a , Seoul National University Hospital, Seoul, Korea
Abstract
Anti-LGI1 (leucine-rich glioma inactivated-1) antibody encephalitis is one of autoimmune encephalitis. We report a 66-year-old man who presented with frequent, brief dystonic seizures which involve predominantly ipsilateral face and arm without cognitive impairment. Brain MRI showed normal finding. Serum and CSF tests revealed anti-LGI1 antibody. His symptom was not relieved by antiepileptic drugs, but completely controlled after immunotherapy. This case indicates that recognition of the brief, dystonic seizures should do tests for anti-LGI1 antibodies. Key Words: Autoimmune encephalitis, LGI1, Voltage gated potassium channel
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Anti-LGI1 Antibody Limbic Encephalitis Presented with Amnestic Mild Cognitive Impairment  2016 February;34(1)