Progressive Multifocal Leukoencephalopathy Presenting as Viral
Encephalitis in a Healthy Adult

J Korean Neurol Assoc > Volume 30(3); 2012 > Article

Journal of the Korean Neurological Association 2012;30(3): 218-221.

건강한 성인에서 바이러스뇌염으로 발현한 진행다초점백질뇌병증

나주영, 이원구 김광수

고신대학교 의과대학 신경과학교실

Progressive Multifocal Leukoencephalopathy Presenting as Viral Encephalitis in a Healthy Adult

Ju Young Na

Department of Neurology, Kosin University College of Medicine, Busan, Korea

Abstract

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by the human polyomavirus JC virus. PML mainly occurs in immunocompromised patients. A 36-year-old man with no evidence of immunosuppresion presented seizures. MRI scans of brain showed multifocal lesions in the cerebral white matters. JC virus DNA was positive in the cerebrospinal fluid examined by JC virus PCR. We report a rare case of PML presenting as viral encephalitis that occurred in a healthy adult person. Key Words: JC virus, Progressive multifocal leukoencephalopathy, Viral encephalitis