Severe Amnestic Dementia With Motor Neuron Disease

J Korean Neurol Assoc > Volume 27(1); 2009 > Article

Journal of the Korean Neurological Association 2009;27(1): 64-67.

운동신경세포병을 동반한 심한 기억상실성 치매

김은주, 안보영 김대성 김성장a 나덕렬b 김재승c 이재홍d

부산대학교 의과대학 신경과학교실, 핵의학교실a, 성균관대학교 의과대학 신경과학교실b, 울산대학교 의과대학 핵의학교실c, 신경과학교실d

Severe Amnestic Dementia With Motor Neuron Disease

Eun-Joo Kim

Department of Neurology, Department of Nuclear Medicinea, Pusan National University School of Medicine and Medical Research Institute, Busan, Korea; Department of Neurologyb, Sungkyunkwan University School of Medicine, Seoul, Korea; Department of Nuclear Medicinec, Department of Neurologyd, University of Ulsan College of Medicine, Seoul, Korea

Abstract

Motor neuron disease (MND) and frontotemporal dementia often appear together. We report on a 74-year-old woman who presented with a 18-month history of memory deterioration and MND. Her initial clinical diagnosis was probable Alzheimer’s disease (AD) coexisting with MND. We conducted 11C-labeled Pittsburgh Compound-B positron-emission tomography (11C?PIB PET) to discriminate AD from other degenerative dementia, the results from which were negative for amyloid deposition. Key Words: Motor neuron disease, Alzheimer’s disease, 11C-labeled Pittsburgh Compound-B positron-emission tomography (11C?PIB PET)