Acute Marchiafava-Bignami Disease With Typical White Matter Involvement on Diffusion Weighted MRI

J Korean Neurol Assoc > Volume 26(4); 2008 > Article

Journal of the Korean Neurological Association 2008;26(4): 376-378.

확산강조영상에서 전형적인 백질 부위 침범을 보인급성 Marchiafava-Bignami병

신혜은, 김재국 조성래 정성해 윤수진

을지대학교 의과대학 을지대학병원 신경과학교실

Acute Marchiafava-Bignami Disease With Typical White Matter Involvement on Diffusion Weighted MRI

Hey Eun Shin

Department of Neurology, Eulji University School of Medicine, Daejeon, Korea

Abstract

Marchiafava-Bignami disease (MBD) is characterized by cerebral white matter lesions associated with chronic alcoholism. Premortem diagnosis of MBD is usually based on history and clinical manifestations. We report a case of acute MBD in which diffusion-weighted MRI (DWI) showed high signal intensities along the white matter including the corpus callosum. DWI may be useful in premortem diagnosis of acute MBD.KeyWords:Marchiafava-Bignami disease, White matter disease, DWI