Transient Global Amnesia With Unilateral Hippocampal Lesionsand Contralateral Temporal Spikes

J Korean Neurol Assoc > Volume 26(3); 2008 > Article

Journal of the Korean Neurological Association 2008;26(3): 250-253.

편측 해마 병변과 반대측 측두엽 발작파를동시에 보인 일과성전기억상실

임재성, 양영순a 박기홍 오세호 김지수 김상윤 박성호

서울대학교 의과대학 신경과학교실 분당서울대학교병원 신경과, 순천향대학교 의과대학 신경과학교실a

Transient Global Amnesia With Unilateral Hippocampal Lesionsand Contralateral Temporal Spikes

Jae-Sung Lim

Department of Neurology College of Medicine Seoul National University, Seoul National University Bundang Hospital, Seongnam, Korea; Department of Neurology College of Medicine Soonchunhyang Universitya, Seoul, Korea

Abstract

Recently, various diagnostic modalities revealed the characteristic abnormalities in transient global amnesia (TGA). We described two TGA patients with focal lesions in the right hippocampus. One patient showed bilateral temporal spike-and-wave on EEG and contralateral temporal hyperperfusion on SPECT. The other exhibited contralateral temporal sharp waves and ipsilateral temporal hypoperfusion. Our patients suggest that bilateral dysfunction of the medial temporal lobe is important for developing TGA. Multimodal diagnostic approach is required to clarify this phenomenon.KeyWords:Transient global amnesia, EEG, MRI