Middle Cerebral Artery Infarction Associated with Osler-Weber-Rendu Disease

J Korean Neurol Assoc > Volume 25(3); 2007 > Article

Journal of the Korean Neurological Association 2007;25(3): 402-405.

Osler-Weber-Rendu병과 연관된 중뇌동맥경색증

문찬오, 한석원 곽재규 정영식 손종희 이상무 최휘철

한림대학교 의과대학 신경과학교실

Middle Cerebral Artery Infarction Associated with Osler-Weber-Rendu Disease

Chan O Moon

Department of Neurology, Hallym University, College of Medicine, Chunchon, Korea

Abstract

Osler-Weber-Rendu disease is characterized by epistaxis, cutaneous telangiectasia, and visceral arteriovenous malformations (AVMs). A 65-year-old male with recurrent epistaxis, old infarction and recent multiple rib fractures caused by a bicycle accident had middle cerebral thromboembolic infarctions when he stopped taking clopidogrel due to massive epistaxis and hemopneumothorax. On examinations, there was no focal cerebral stenosis, but there were telangiectasia, pulmonary and hepatic AVMs. A suspicious Osler-Weber-Rendu disease patient should be evaluated by proper screening and regular follow-up to minimize serious sequelae such as thromboembolic stroke. KeyWords:Osler-weber-Rendu disease, Cerebral Infarction