A Case of Hyperprolactinemia with Galactorrhea Induced by Carbamazepine

J Korean Neurol Assoc > Volume 25(3); 2007 > Article

Journal of the Korean Neurological Association 2007;25(3): 381-382.

카바마제핀 복용 후 발생한 유루증을 동반한 고프로락틴혈증 1예

박천훈, 김선영 윤승환 이종윤 정연경 고임석 조필자

국립의료원 신경과학교실

A Case of Hyperprolactinemia with Galactorrhea Induced by Carbamazepine

Chun-Hoon Park

Department of Neurology, National Medical Center, Seoul, Korea

Abstract

Carbamazepine (CBZ) may alter the secretion of prolactin (PRL), however, there is no report about hyperprolactinemia with galactorrhea induced by CBZ medication. A 30-year-old woman presented with galactorrhea. She had been treated with CBZ for three years and hormonal study revealed increased serum PRL levels. Sella MRI showed no evidence of pituitary lesion. Two months after changing CBZ to oxcarbazepine, galatorrhea was improved and the serum PRL level was normalized. KeyWords:Carbamazepine, Hyperprolactinemia, Galactorrhea