A Case of Acute Respiratory Muscle Weakness Complicated by Sjogren Syndrome

J Korean Neurol Assoc > Volume 25(2); 2007 > Article

Journal of the Korean Neurological Association 2007;25(2): 240-243.

급성 호흡근 마비를 보인 Sjogren 증후군 1예

남효석, 서범천a 조정희b 정연경c 김승민d 선우일남d

아주대학교 의과대학 신경과학교실, 성균관대학교 의과대학 강북삼성병원 신경과a, 국민건강보험공단 일산병원 신경과b, 국립의료원 신경과c, 연세대학교 의과대학 신경과학교실d

A Case of Acute Respiratory Muscle Weakness Complicated by Sjogren Syndrome

Hyo Suk Nam

Department of Neurology, Ajou University School of Medicine, Suwon, Korea Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicinea, Seoul, Korea Department of Neurology, National Health Insurance Coorporation Ilsan Hospitalb, Goyang, Korea Department of Neurology, National Medical Centerc, Seoul, Korea Department of Neurology, Yonsei University College of Medicined, Seoul, Korea

Abstract

Sjogren syndrome is a chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands resulting in dry mouth and eyes. Approximately one-third of patients present with systemic manifestations, but respiratory muscle involvements have been rarely reported. We report a case of acute respiratory failure complicated by primary Sjogren syndrome. Muscle biopsy revealed perivascular lymphocytic infiltrations. Corticosteroid therapy improved respiratory muscle weakness. Sjogren syndrome should be considered as one of the underlying diseases causing acute respiratory failure. KeyWords:Sjogren syndrome, Respiratory paralysis, Myopathies