J Korean Neurol Assoc > Volume 24(3); 2006 > Article
Journal of the Korean Neurological Association 2006;24(3): 204-209.
앞순환계에 폐쇄성 혈관 질환이 있는 환자에서 기저동맥의 혈관운동반응성
박태환, 박수현 윤영철 권오상
중앙대학교 의과대학 신경과학교실
Vasomotor Reactivity of the Basilar Artery in Patients with Occlusive Vascular Diseases in the Anterior Circulation
Tai Hwan Park
Department of Neurology, Chungang University College of Medicine, Seoul, Korea
Abstract
Background: The basilar artery (BA) may act as an important intracranial collateral to supply hypoperfused anterior circulation. We examined the basilar reserve capacity by using transcranial Doppler sonography (TCD) in patients with occlusive vascular diseases in the anterior circulation (OAC) to determine whether vasomotor reactivity (VMR) of the BA can be affected by the presence of OAC.
Methods: Twenty-five patients were given an MRI including an MRA for minor ischemic symptoms, headache, or dizziness and were divided into two groups according to the presence of OAC. The OAC included occlusions of either the internal carotid artery (ICA) or M1 segment of the middle cerebral artery (MCA). The VMR to hypercapnea was calculated by means of the breath-holding index (BHI). We compared the VMR of the BA between those with and without OAC.
Results: Patients with OAC (n=8) showed significantly reduced basilar VMR, compared to that of patients without OAC (n=17) (0.57±0.49 versus 1.36±0.47, P=0.001). The baseline mean flow velocity of BA was also higher in patients with OAC (70.6±24.2cm/s) than those without (38.8±11.5 cm/s). However, the baseline pulsatility index did not show differences between patients with and without OAC.
Conclusions: Patients with OAC showed decreased VMR of BA, which can be an easily applicable and useful TCD index for assessing the hemodynamic status in patients with OAC.KeyWords:Vasomotor reactivity, Tanscranial doppler sonography, Basilar artery


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