Periodic Sharp Wave Complexes observed by Repetitive EEGs in a Patient with Probable Sporadic Creutzfeldt-Jacob Disease

J Korean Neurol Assoc > Volume 24(2); 2006 > Article

Journal of the Korean Neurological Association 2006;24(2): 157-160.

산발성 크로이츠펠트-야콥병 환자에서 반복적 뇌파 검사를 통해 관찰된 주기예파복합체

하연수, 김정연 한상원 백종삼 박재현

인제대학교 의과대학 상계백병원 신경과

Periodic Sharp Wave Complexes observed by Repetitive EEGs in a Patient with Probable Sporadic Creutzfeldt-Jacob Disease

Yeon Soo Ha, M.D.

Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea

Abstract

The periodic sharp wave complexes are the most characteristic EEG abnormalities in sCJD. We report the serial EEG findings in a patient with probable sCJD. The initial EEG showed diffuse theta and delta slowings only. However, it changed to the typical periodic sharp wave complexes according to the worsening clinical state. These changes occurred during a short-term interval. The serial EEGs within the short-term interval will be helpful for the earlier diagnosis of sCJD.KeyWords:Creutzfeldt-Jacob disease, Electroencephalography