A Case of Cryptococcal Meningitis with Bilateral Internuclear Ophthalmoplegia and Ptosis

J Korean Neurol Assoc > Volume 23(4); 2005 > Article

Journal of the Korean Neurological Association 2005;23(4): 557-560.

양측성 핵간안근마비와 안검하수를 동반한 크립토콕쿠스 뇌수막염 1예

김선혜, 권오영a,b 손승남a 김지은a 최지혜a 박기종a,b 최낙천a,b 임병훈a,b

경상대학교 의과대학 신경과학교실a, 경상대학교 건강과학연구원b

A Case of Cryptococcal Meningitis with Bilateral Internuclear Ophthalmoplegia and Ptosis

Seonhye Kim

Department of Neurology, Gyeongsang National University College of Medicinea, Jinju; Gyeongsang Institute of Health Science, Gyeongsang National Universityb, Jinju, Korea

Abstract

A 73-year-old woman with long-term steroid medication for arthralgia, suffered a sudden decrement of mental status, bilateral internuclear ophthalmoplegia and ptosis. T2-weighted MR images revealed high signals in the midbrain and both thalami. In cerebrospinal fluid studies, a test for cryptococcal antigen was positive and Cryptococcus neoformans was cultured. Bilateral internuclear ophthalmoplegia and ptosis may develop in cryptococcal meningitis from ischemic complications. KeyWords:Cryptococcal meningitis, Internuclear ophthalmoplegia